A predictive tool for early identification of moderate-to-severe pain following open colorectal surgery in older adults: a retrospective cohort study
Authors' conclusion
We developed and validated a nomogram incorporating psychosocial, inflammatory, and procedural factors to predict moderate-to-severe postoperative pain.
Study context
- Population
- Patients aged ≥ 60 years undergoing elective open colorectal surgery
- Participants
- 300 patients
- Outcome
- Moderate-to-severe postoperative pain (NRS ≥ 4)
- Follow-up
- Within 24 h
Methodological detailsprediction model development and internal validation, nomogram
- Prediction model development and internal validation
- Nomogram
Main finding
As reported in the abstract
Moderate-to-severe pain and model performance
Incidence of moderate-to-severe pain
120
40.0%
Independent predictors (P < 0.05): GAD-7, PHQ-9, MMSE, MOS-SSS, CRP, operative duration, Miles procedure
7
AUC, training
0.79
AUC, validation
0.77
Observational data: associations, not effects.
Further findings
Characteristics of patients with moderate-to-severe pain
- Older, higher preoperative Numerical Rating Scale (NRS) and CRP, worse psychosocial and cognitive scores (P < 0.01)
Original publication
A predictive tool for early identification of moderate-to-severe pain following open colorectal surgery in older adults: a retrospective cohort study. Perioper Med (Lond). Published 8 October 2025. doi:10.
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