Hemodynamics, fluids & transfusion
A prospective, observational study of non-invasive venous waveform analysis (NIVA) for the detection of acute low volume blood loss in humans
Authors' conclusion
This study supports the potential application of NIVA in the detection of acute low-volume human blood loss.
Study context
- Population
- American Red Cross (ARC)-approved whole blood donors at an American Red Cross donation centervenous waveforms captured
- Participants
- 33 donors
- Outcome
- Detection of low-volume blood loss by change in IVAN
Methodological detailssingle donation centre
- Single donation centre
Main finding
As reported in the abstract
Detection of blood loss by delta IVAN
| Group | AUC, 200 mL blood loss | AUC, 500 mL blood loss |
|---|---|---|
| NIVA | 0.65 | 0.91 |
NIVA
AUC, 200 mL blood loss0.65
AUC, 500 mL blood loss0.91
- Significant decrease in IntraVAscular Number (IVAN) after 200 mL (3-4 % blood volume) of whole blood donation
- P < 0.05
Observational data: associations, not effects.
Original publication
A prospective, observational study of non-invasive venous waveform analysis (NIVA) for the detection of acute low volume blood loss in humans. J Clin Anesth. Published 17 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →