Anesthetic drugs & techniques

A systematic review on the use of sevoflurane in the management of status asthmaticus in adults

Crit CarePublished Systematic review of case reports, case series and conference abstracts

Authors' conclusion

The systematic review suggests sevoflurane can be a valuable treatment option in SA.

Study context

Population
Adults with status asthmaticus (SA)13 publications
Participants
18 adults
Outcome
Clinical status with sevoflurane
Methodological detailsno randomised trials available
  • No randomised trials available

Pooled result

As reported in the abstract

Patients with improvement in clinical status with sevoflurane

16

Required escalation to extracorporeal membrane oxygenation (ECMO)

1

Did not survive

1

Further pooled results

Pre-sevoflurane status

Most patients required intubation despite best medical management before sevoflurane; high airway pressures and respiratory acidosis apparent

Original publication

A systematic review on the use of sevoflurane in the management of status asthmaticus in adults. Crit Care. Published 14 October 2024. doi:10.1186/s13054-024-05122-8

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