ICU sedation, delirium & recovery
Accuracy of a Risk Alert Threshold for ICU Hypoglycemia: Retrospective Analysis of Alert Performance and Association With Clinical Deterioration Events
Authors' conclusion
Alerts generated by a validated ICU hypoglycemia prediction model had a positive predictive value of 13.7% for real-world hypoglycemia events.
Study context
- Population
- Critically ill adults admitted to ICU, University of Virginia Medical Center, June 2020–April 2021
- Outcome
- Level 1 hypoglycemia correctly predicted
- Follow-up
- ≥1 and ≤12 hours after alert
Methodological detailsdiagnostic accuracy study, single-centre, real-world testing, proof-of-concept
- Diagnostic accuracy study
- Single-centre
- Real-world testing
- Proof-of-concept
Main finding
As reported in the abstract
| Group | Value | PPV |
|---|---|---|
| Hypoglycemia risk alert | 48 events | 13.7% |
Hypoglycemia risk alert
Value48 events
PPV13.7%
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Level 2 hypoglycemia among correctly predicted cases | Hypoglycemia risk alert 43.8% |
- Level 2 hypoglycemia among correctly predicted cases: of 48 cases
Clinical deterioration events ≥1 and ≤12 hours after alert
- MI
- 3
- Medical emergency team call
- 1
- Deaths
- 19
- Arrhythmias
- 20
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Accuracy of a Risk Alert Threshold for ICU Hypoglycemia: Retrospective Analysis of Alert Performance and Association With Clinical Deterioration Events. Crit Care Med. Published 3 November 2022. doi:10.
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