Paediatric anaesthesia & critical care
Accuracy of Bispectral Index™ monitoring in an alternative nasal position in pediatric patients under general anesthesia: a prospective observational study
Main finding · Agreement between nasal and frontal BIS valuesResult — go to the resultMean difference 1.0Authors' conclusion
Bispectral Index values obtained from the nasal region in pediatric patients agreed within ±10 units of the values from conventional frontal placement.
Study context
- Population
- Children aged 4–12 yr undergoing GA with sevoflurane5,049 paired measurements analysed
- Participants
- 40 children
- Exposure
- Nasal vs frontal BIS sensor placement
- Outcome
- Agreement between nasal and frontal BIS values
Methodological detailsmethod-comparison (agreement) study
- Method-comparison (agreement) study
Main finding
As reported in the abstract
Mean difference
1.0
- Concordance correlation coefficient
- 0.88
- Marginal incidence of BIS values exceeding ±10-unit threshold
- 3.9% (95% CI, 2.1% to 5.8%)
Observational data: associations, not effects.
Further findings
BIS values exceeding ±10-unit threshold, emergence (subgroup)
- Marginal incidence
- 6.6% (95% CI, 1.3% to 11.8%)
BIS values exceeding ±10-unit threshold, high-EMG (subgroup)
- Marginal incidence
- 8% (95% CI, 1% to 15%)
BIS values exceeding ±10-unit threshold, age groups (subgroup)
- Similar across age groups
Power spectral density
- Spectral characteristics comparable, with lower total power at the nasal position
Original publication
Accuracy of Bispectral Index™ monitoring in an alternative nasal position in pediatric patients under general anesthesia: a prospective observational study. Can J Anaesth. Published 19 August 2026. doi:10.
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