ICU sedation, delirium & recovery
Accuracy of estimating equations for the assessment of glomerular filtration rate in critically ill patients versus outpatients
Authors' conclusion
All four equations performed poorly in assessing GFR in the critically ill cohort with an unacceptably high error and low accuracy in contrast to the outpatient group.
Study context
- Population
- Critically ill patients and outpatients with normal-to-moderately reduced glomerular filtration rate (GFR)
- Comparison
- Four eGFR equations vs mGFR, in critically ill patients vs outpatients
- Critical caren = Forty-three
- Outpatientsn = 48
- Outcome
- Agreement between mGFR and eGFR (Bland-Altman bias, error) and accuracy (P30, P10)
Methodological detailstwo cohorts
- Two cohorts
Performance
As reported in the abstract
Agreement of 4 eGFR equations (CKD-EPICr, CKD-EPICys C, CKD-EPICr + Cys C, LMCr + Cys C) with mGFR
| Test or model | Bias range (mL/min/1.73 m²) | Error | Accuracy (P30) |
|---|---|---|---|
| Critically ill | −3.6 to 2.8 | 121%-127% | 33%-40% |
| Outpatients | −13.0 to 7.6 | 31%-41% | 67%-96% |
Bias range (mL/min/1.73 m²)
Critically ill−3.6 to 2.8
Outpatients−13.0 to 7.6
Error
Critically ill121%-127%
Outpatients31%-41%
Accuracy (P30)
Critically ill33%-40%
Outpatients67%-96%
Original publication
Accuracy of estimating equations for the assessment of glomerular filtration rate in critically ill patients versus outpatients. Acta Anaesthesiol Scand. Published 22 October 2024. doi:10.
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