Activities of daily living, physical activity, and care situation in chronic critical illness survivors one year after disease onset: A prospective cohort study
Authors' conclusion
One year after CCI, most patients continued to exhibit functional impairment and substantial restrictions in independent living. The presence of CIP/CIM worsened outcomes.
Study context
- Population
- Patients with chronic critical illness (CCI) and ≥ 5 days of mechanical ventilation who underwent inpatient neurological rehabilitation (CINAMOPS)
- Participants
- 204 patients
- Exposure
- Pre-hospitalization vs one-year follow-up; CIP/CIM vs no CIP/CIM
- Outcome
- ADL, IADL, physical activity and disability
- Follow-up
- One year after onset of critical illness
Main finding
As reported in the abstract
WHODAS-12 score (%)
39 ± 26 %
Moderate to severe disability
64 %
Independent in personal care
62 %
Able to manage household tasks
36 %
Observational data: associations, not effects.
Further findings
Correlation with health-related quality of life (HRQoL)
- Disability and functional dependence correlate with HRQoL
Employment
- Of those previously employed, nearly half remained on sick leave
CIP/CIM vs no CIP/CIM
- CIP/CIM associated with worse functional outcomes and greater therapy needs
Original publication
Activities of daily living, physical activity, and care situation in chronic critical illness survivors one year after disease onset: A prospective cohort study. J Crit Care. Published 6 December 2025. doi:10.
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