ICU sedation, delirium & recovery

Long-term recovery of sensorimotor functions and prediction of participation in survivors of critical illness: a prospective cohort study

J Intensive CarePublished Prospective cohort study

Authors' conclusion

We observed significant improvements in sensorimotor function, albeit with lingering deficits in sensation, strength, balance, dexterity and participation. Sensorimotor functions at rehabilitation start have limited explanatory power in predicting participation 1.5 years after disease onset.

Study context

Population
Survivors of critical illness mechanically ventilated ≥ 5 days on the ICU and admitted with weakness to neurorehabilitationmedian age 63 (54–73) years
Participants
250 survivors
Outcome
Long-term sensorimotor recovery (sensation, muscle strength, balance, walking, dexterity) and participation in daily life (Reintegration to Normal Living Index)
Follow-up
1.5 years after illness onset
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Good participation (≥ 75%) achieved 1.5 years after critical illness onset

60.2%

Observational data: associations, not effects.

Further findings

Prediction of participation by sensorimotor assessments at rehabilitation admission (Mini-BESTest, Box-and-Block-Test, Five-Times-Sit-to-Stand-Test, Medical Research Council score)

Predictive model R2
0.157
P
P < 0.001

Extended regression model (depression, duration of mechanical ventilation, cognitive function, Mini-BESTest, comorbidities, sex, cerebral lesion)

Model R2
0.357
P
P < 0.001

Original publication

Long-term recovery of sensorimotor functions and prediction of participation in survivors of critical illness: a prospective cohort study. J Intensive Care. Published 8 September 2025. doi:10.1186/s40560-025-00808-9

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