Cardiothoracic & vascular anesthesia
Acute Kidney Injury After Heart Transplantation: Risk Factors and Clinical Outcomes
Study context
- Population
- Patients who underwent heart transplantation (OHT) between 2012 and 2021 at a maximum-care university hospital189 analysed
- Participants
- 264 patients
- Exposure
- Donor and recipient risk factors for renal-replacement therapy (RRT) after OHT
- Outcome
- Posttransplant AKI with RRT
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Acute kidney injury (AKI) with RRT, n (%)
- 123 (65.1%)
- Preoperative BMI >25 kg/m², OR
- 4.74, p < 0.001
- Preoperative creatinine, OR per mg/dL increase
- 3.44, p = 0.004
- Intraoperative RBC units, OR
- 2.31, p = 0.041
- Ischemia time, OR per hour increase
- 1.77, p = 0.004
- Pretransplant renin-angiotensin-aldosterone system blockers, OR
- 0.36, p = 0.013
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Mortality, RRT vs no RRT | 6.9 (2.1–22.6) | P = 0.001 | |
| 0.050.21520Hazard ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Acute Kidney Injury After Heart Transplantation: Risk Factors and Clinical Outcomes. J Cardiothorac Vasc Anesth. Published 26 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →