Cardiothoracic & vascular anesthesia
Acute Normovolemic Hemodilution Versus Norepinephrine Infusion During Autologous Blood Donation in Coronary Artery Bypass Graft Surgery: A Prospective Randomized Study
Authors' conclusion
Norepinephrine infusion demonstrated hemodynamic equivalence to ANH in the setting of autologous blood donation during coronary artery bypass graft surgery.
Study context
- Population
- Patients undergoing CABG surgery with autologous blood donation
- Participants
- 40 patients
- Comparison
- NA vs acute normovolemic hemodilution (ANH)
- Primary endpoint
- Comparison of cardiac cycle efficiency (CCE) changes between groups
Methodological detailsprospective, single-centre
- Prospective
- Single-centre
Primary result
As reported in the abstract
Change in CCE
ANH
0.20
± 0.51
NA
0.5
± 0.57
P = 0.373
Secondary outcomes
Cardiac index, stroke volume index, metabolic markers
- No relevant differences between groups
- P > 0.05
Dynamic preload parameters
- Expected physiological patterns in NA group, consistent with volume-sparing circulatory support
ICU and hospital LOS
- No difference between groups
Safety
- No patients experienced AKI
Original publication
Acute Normovolemic Hemodilution Versus Norepinephrine Infusion During Autologous Blood Donation in Coronary Artery Bypass Graft Surgery: A Prospective Randomized Study. J Cardiothorac Vasc Anesth. Published 28 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →