Cardiothoracic & vascular anesthesia
Hemodynamic Response to Intubation With 4 Different Laryngoscopes in Coronary Artery Bypass Graft Surgery: A Randomized Trial
Authors' conclusion
Videolaryngoscopes conferred no hemodynamic advantage over direct laryngoscopy during intubation in deeply anesthetized patients undergoing CABG.
Study context
- Population
- Adults scheduled for elective coronary artery bypass graft (CABG) with no anticipated difficult airway, under standardized deep anesthesia
- Participants
- 112 adults
- Comparison
- Macintosh laryngoscope vs C-MAC, EzVision or McGrath videolaryngoscope
- Primary endpoint
- Hemodynamic stress response: ΔMAP and ΔHR between after induction before NMB (T2) and 1 minute after tracheal intubation (T4)
- Follow-up
- 1 minute after tracheal intubation
Methodological detailsprospective, single-centre, University-affiliated tertiary care hospital
- Prospective
- Single-centre
- University-affiliated tertiary care hospital
Primary result
As reported in the abstract
ΔMAP · T2 to T4
Macintosh
20.8
mean · SD 19.4 · mmHg
C-MAC
26.3
mean · SD 13.6 · mmHg
EzVision
21.8
mean · SD 12.4 · mmHg
McGrath
28.4
mean · SD 11.9 · mmHg
P = 0.168
Further findings
Hemodynamic stress response (MAP increase ≥10 mmHg and/or HR increase ≥10 bpm) · across 4 groups
P = 0.653
Intubation time · across 4 groups
P < 0.001
Mean, bpm
| Outcome | Macintosh | C-MAC | EzVision | McGrath | P value |
|---|---|---|---|---|---|
| ΔHR (co-primary) · T2 to T4Across 4 groups | 7.4 (SD 8.2) | 6.1 (SD 10.6) | 8.6 (SD 16.4) | 7.5 (SD 7.7) | P = 0.844 |
Intubation success
- Similar across groups
Safety
- Complication profiles similar across groups
Original publication
Hemodynamic Response to Intubation With 4 Different Laryngoscopes in Coronary Artery Bypass Graft Surgery: A Randomized Trial. J Cardiothorac Vasc Anesth. Published 5 April 2026. doi:10.
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