Adjustment of positive end‐expiratory pressure based on body mass index during general anaesthesia: a randomised controlled trial*
Authors' conclusion
In patients without major pulmonary disease who were undergoing non-cardiothoracic surgeries with tracheal intubation, adjusting PEEP based on a calculation of BMI/3 improved lung mechanics and reduced postoperative loss of lung aeration.
Study context
- Population
- Adults undergoing surgery under GA with tracheal intubation
- Participants
- 60 adults
- Comparison
- PEEP set by BMI vs standard PEEP 5 cmH2O
Methodological detailspatient-blinded, single-centre, superiority, two parallel groups
- Patient-blinded
- Single-centre
- Superiority
- Two parallel groups
Primary result
As reported in the abstract
Driving pressure
P = 0.027
Further findings
Respiratory system compliance
P = 0.020
Postoperative loss of lung aeration (lung ultrasound)
- Reduced in the BMI/3 group
Supplemental oxygen, new atelectasis, SpO2 on PACU arrival
- Less supplemental oxygen, less new atelectasis and higher oxygen saturation in the BMI-adjusted group
Original publication
Adjustment of positive end‐expiratory pressure based on body mass index during general anaesthesia: a randomised controlled trial*. Anaesthesia. Published 23 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →