Respiratory failure & ventilation

Admission serum sodium and osmolarity are not associated with the occurrence or outcomes of acute respiratory distress syndrome in critically ill

J Crit CarePublished Retrospective cohort study

Authors' conclusion

Admission serum sodium or serum osmolarity were not associated with the occurrence or outcomes of ARDS in ICU.

Study context

Population
All admissions to medical, surgical and multidisciplinary ICUs, Mayo Clinic, Rochester, 2009–2019
Participants
50,498 admissions
Exposure
Admission serum sodium and calculated serum osmolarity and ARDS
Outcome
Occurrence of ARDS (validated computerized search strategy)
Methodological detailssingle-centre, multivariable logistic regression
  • Single-centre
  • Multivariable logistic regression

Main finding

As reported in the abstract

Occurrence of ARDS
Adjusted odds ratio (95% CI)
Admission serum sodium
0.95(0.86–1.05)
Calculated serum osmolarity
1.03(1.00–1.07)

Observational data: associations, not effects.

Further findings

OutcomeValues
Outcomes of ARDS in patients who developed ARDSDeveloped ARDS during ICU stay 1560 events

Outcomes of ARDS in patients who developed ARDS

Serum sodium and osmolarity not significantly associated with their outcomes

Original publication

Admission serum sodium and osmolarity are not associated with the occurrence or outcomes of acute respiratory distress syndrome in critically ill. J Crit Care. Published 28 October 2022. doi:10.1016/j.jcrc.2022.154179

Composed by AI from the published abstract and checked against it. How Briefs are made →

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