Cardiothoracic & vascular anesthesia
Adoption of a novel biomarker-guided quality improvement treatment bundle for patients with subclinical acute kidney injury after cardiac surgery: An implementation study
Authors' conclusion
This implementation science study demonstrates that this biomarker-guided renal care bundle is deliverable after cardiac surgery, outside of a research setting. Our findings show that the intervention is acceptable, feasible and appropriate, which is strongly supported by its 'perceived effectiveness'.
Study context
- Population
- Adults after cardiac surgery in the cardiac ICU and clinicians (medical and surgical consultants, nursing staff), two tertiary cardiac surgical centres, London, UK, July 2021–February 202249 survey respondents
- Participants
- 176 adults
- Outcome
- Implementation assessed using Weiner's adoption metrics and Sekhon's theoretical framework of acceptability
Methodological detailstwo-centre, biomarker-guided renal care bundle, clinician implementation survey
- Two-centre
- Biomarker-guided renal care bundle
- Clinician implementation survey
Main finding
As reported in the abstract
- Weiner's adoption metrics: median acceptability, appropriateness and feasibility scores (out of 5)
- 4
- Sekhon's framework: median score of all domains (out of 5)
- 4
- Highest domain: Perceived Effectiveness (mean)
- 4.0
- Lowest domain: Burden (mean)
- 3.4
- Lowest domain: Opportunity Costs (mean)
- 3.4
Observational data: associations, not effects.
Further findings
Raised biomarker level requiring the renal care bundle
- Patients with raised biomarker level (n = 61)
- 34.7%
- Mean bundle items delivered (out of 6)
- 4.4
Original publication
Adoption of a novel biomarker-guided quality improvement treatment bundle for patients with subclinical acute kidney injury after cardiac surgery: An implementation study. Eur J Anaesthesiol. Published 21 November 2025. doi:10.
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