Agreement between cardiac output measurements by pulse wave analysis using the Pressure Recording Analytical Method and transthoracic echocardiography in patients with veno-venous extracorporeal membrane oxygenation therapy: An observational method comparison
An erratum to this article was published (Eur J Anaesthesiol, 1 Nov 2023 ↗)
Authors' conclusion
The agreement between PRAM-CO and TTE-CO is clinically acceptable in adult patients with vvECMO therapy.
Study context
- Population
- Adults with respiratory failure requiring veno-venous extracorporeal membrane oxygenation (vvECMO), ICU of a German university hospital, March–December 202129 COVID-19 related
- Participants
- 31 adults
- Exposure
- Cardiac output (CO) by Pressure Recording Analytical Method (PRAM) vs transthoracic echocardiography
- Outcome
- Agreement between PRAM-CO and TTE-CO (Bland-Altman analysis and percentage error; PE <30% clinically acceptable)
Methodological detailssingle-centre, PRAM-CO and TTE-CO measured simultaneously at two time points per patient, ≥20 min apart
- Single-centre
- PRAM-CO and TTE-CO measured simultaneously at two time points per patient, ≥20 min apart
Main finding
CO agreement
Mean of the differences
0.09 l min −1
95% CI −1.34 to 1.51
By group
PRAM-CO vs TTE-CO
mean of the differences 0.09 l min −1 (95% CI −1.34 to 1.51)
As reported in the abstract
- Percentage error
- 21%
Observational data: associations, not effects.
Original publication
Agreement between cardiac output measurements by pulse wave analysis using the Pressure Recording Analytical Method and transthoracic echocardiography in patients with veno-venous extracorporeal membrane oxygenation therapy: An observational method comparison. Eur J Anaesthesiol. Published 12 April 2023. doi:10. 1097/ eja. 0000000000001828
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