Organ support & nutrition

Agreement between cardiac output measurements by pulse wave analysis using the Pressure Recording Analytical Method and transthoracic echocardiography in patients with veno-venous extracorporeal membrane oxygenation therapy: An observational method comparison

Eur J AnaesthesiolPublished Prospective observational method comparison study

An erratum to this article was published (Eur J Anaesthesiol, 1 Nov 2023 ↗)

Authors' conclusion

The agreement between PRAM-CO and TTE-CO is clinically acceptable in adult patients with vvECMO therapy.

Study context

Population
Adults with respiratory failure requiring veno-venous extracorporeal membrane oxygenation (vvECMO), ICU of a German university hospital, March–December 202129 COVID-19 related
Participants
31 adults
Exposure
Cardiac output (CO) by Pressure Recording Analytical Method (PRAM) vs transthoracic echocardiography
Outcome
Agreement between PRAM-CO and TTE-CO (Bland-Altman analysis and percentage error; PE <30% clinically acceptable)
Methodological detailssingle-centre, PRAM-CO and TTE-CO measured simultaneously at two time points per patient, ≥20 min apart
  • Single-centre
  • PRAM-CO and TTE-CO measured simultaneously at two time points per patient, ≥20 min apart

Main finding

CO agreement

Mean of the differences

0.09 l min −1

95% CI −1.34 to 1.51

By group

PRAM-CO vs TTE-CO
mean of the differences 0.09 l min −1 (95% CI −1.34 to 1.51)

As reported in the abstract

Percentage error
21%

Observational data: associations, not effects.

Original publication

Agreement between cardiac output measurements by pulse wave analysis using the Pressure Recording Analytical Method and transthoracic echocardiography in patients with veno-venous extracorporeal membrane oxygenation therapy: An observational method comparison. Eur J Anaesthesiol. Published 12 April 2023. doi:10.1097/eja.0000000000001828

Composed by AI from the published abstract and checked against it. How Briefs are made →

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