Alactic base excess is an independent predictor of death in sepsis: A propensity score analysis
Main finding · MortalityResult — go to the resultAdjusted hazard ratio 1.43 95% CI 1.02–2.01Authors' conclusion
Negative ABE is an independent predictor of in-hospital mortality in septic patients with and without renal dysfunction.
Study context
- Population
- Patients with sepsis and septic shock, with and without renal dysfunction
- Participants
- 1,178 patients
- Exposure
- Negative alactic base excess (ABE) vs neutral ABE
- Outcome
- Mortality
Methodological detailspropensity score analysis, inverse probability weighting
- Propensity score analysis
- Inverse probability weighting
Main finding
As reported in the abstract
Adjusted hazard ratio
1.43
95% CI 1.02–2.01
Negative ABE vs Neutral ABE
adjusted HR 1.43 (95% CI 1.02–2.01)
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted HR (95% CI) | |
|---|---|---|
| Mortality, GFR > 60 mL/min/1.73 m² (subgroup, n = 493)Negative ABE vs Neutral ABE · stratified analysis | 2.43 (1.07–5.53) | |
| 0.20.5125Adjusted hazard ratio (log scale) |
Original publication
Alactic base excess is an independent predictor of death in sepsis: A propensity score analysis. J Crit Care. Published 12 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →