Albumin administration in septic shock—Protocol for post‐hoc analyses of data from a multicentre RCT
Study context
- Population
- Adult ICU patients with septic shock in the CLASSIC RCTCLASSIC RCT
- Participants
- 1,554 patients
- Primary endpoint
- Association of baseline characteristics or trial site with IV albumin administration during ICU stay (Cox models with competing events)
Methodological detailsexploratory, multicentre, Models adjusted for CLASSIC allocation (restrictive vs standard intravenous (IV) fluid); competing events death, ICU discharge, loss-to-follow-up, Results as HR with 95% CI; interactions by likelihood ratio tests; all results exploratory
- Exploratory
- Multicentre
- Models adjusted for CLASSIC allocation (restrictive vs standard IV fluid); competing events death, ICU discharge, loss-to-follow-up
- Results as HR with 95% CI; interactions by likelihood ratio tests; all results exploratory
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Albumin administration in septic shock—Protocol for post‐hoc analyses of data from a multicentre RCT. Acta Anaesthesiol Scand. Published 29 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →