Aspiration pneumonia in the world's most aged society: age-stratified ICU management and outcomes from a nationwide Japanese registry
Authors' conclusion
Older patients with aspiration pneumonia had higher illness severity yet received less MV, and had higher in-hospital mortality and lower home discharge rates.
Study context
- Population
- Adults ≥ 18 years admitted to Japanese ICUs with a primary diagnosis of aspiration pneumonia, JIPAD registry, 2015–2023
- Participants
- 3,906 eligible ICU admissions
- Exposure
- Age groups 18-64, 65-74, 75-84 and ≥ 85 years
- Outcome
- In-hospital mortality
Methodological detailsmulticentre, observational, nationwide registry
- Multicentre
- Observational
- Nationwide registry
Main finding
As reported in the abstract
- Overall in-hospital mortality
- 28.3%
Observational data: associations, not effects.
Further findings
Invasive MV use
| Outcome | 18-64 years | 65-74 years | 75-84 years | ≥ 85 years |
|---|---|---|---|---|
| Home discharge | 45.2% | — not stated in the abstract | — not stated in the abstract | 19.9% |
| Illness severity at admission (APACHE III score)Median | 74 (IQR 56–91) | — not stated in the abstract | — not stated in the abstract | 96 (IQR 81–120) |
— not stated in the abstract
- Invasive mechanical ventilation (MV) use — Overall invasive MV use
- 68.8%
Invasive MV use
- Probability of MV use decreased with age, particularly > 75 years (exploratory adjusted analyses)
Hospital and ICU LOS (overall)
- Median hospital LOS 32 days (IQR, 16-58)
- 32
- Median ICU LOS 120.4 h (IQR, 54.4-234.8)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Aspiration pneumonia in the world's most aged society: age-stratified ICU management and outcomes from a nationwide Japanese registry. J Intensive Care. Published 1 August 2026. doi:10. 1186/ s40560-026-00923-1
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