Respiratory failure & ventilation

Assessing the accuracy of ChatGPT in interpreting blood gas analysis results ChatGPT-4 in blood gas analysis

J Clin AnesthPublished Prospective observational study

Authors' conclusion

ChatGPT-4 demonstrated potential as a supplementary tool for ABG interpretation in high-demand clinical settings, supporting rapid, reliable decision-making.

Study context

Population
Arterial blood gas (ABG) samples from ICU patients
Participants
400 ABG samples
Exposure
ChatGPT-4 interpretation of ABG results assessed by experienced anesthesiologists
  • ChatGPT-4n = 400
Outcome
Accuracy of ChatGPT-4 in interpreting ABG parameters (potential diagnoses and treatment)
Methodological detailsTwo anesthesiologists independently evaluated the model's predictions
  • Two anesthesiologists independently evaluated the model's predictions

Main finding

As reported in the abstract

Accuracy by ABG parameter
GroupAccuracy pH, oxygenation, sodium, chlorideAccuracy hemoglobinAccuracy bilirubin
ChatGPT-4100 %92.5 %72.5 %

ChatGPT-4

Accuracy pH, oxygenation, sodium, chloride100 %
Accuracy hemoglobin92.5 %
Accuracy bilirubin72.5 %
Overall performance statistically significant across most parameters
P < 0.05

Observational data: associations, not effects.

Safety

Treatment recommendations

Unnecessary bicarbonate treatment recommended in several cases

Original publication

Assessing the accuracy of ChatGPT in interpreting blood gas analysis results ChatGPT-4 in blood gas analysis. J Clin Anesth. Published 21 February 2025. doi:10.1016/j.jclinane.2025.111787

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