Assessing the incidence of hyperoxia and the effectiveness of Oxygen Reserve Index-guided FiO2 titration in hyperoxia prevention
Authors' conclusion
The combined use of SpO2 and ORi has been demonstrated to successfully guide FiO2 titration for optimal oxygenation and reduce hyperoxemia.
Study context
- Population
- Patients undergoing major abdominal surgery
- Comparison
- SpO2 + ORi-guided FiO2 titration vs control
Methodological detailsprospective, single-centre, Health Sciences University İzmir Tepecik Training and Research Hospital, September 1, 2020, to December 1, 2022
- Prospective
- Single-centre
- Health Sciences University İzmir Tepecik Training and Research Hospital, September 1, 2020, to December 1, 2022
Primary result
As reported in the abstract
Moderate hyperoxemia · 3rd hour
Control
31.6%
- Positive linear relationship between PaO2 and ORi in the ORi + SpO2 group (r = 0.758)
- P < 0.001
Further findings
Correlation between PaO2 and ORi (SpO2 + ORi)
- Positive linear relationship of 75.8% (r = 0.758), p < 0.001
PaO2 over time (SpO2 + ORi)
- PaO2 decreased significantly over time with FiO2 titration, p < 0.001
Original publication
Assessing the incidence of hyperoxia and the effectiveness of Oxygen Reserve Index-guided FiO2 titration in hyperoxia prevention. Perioper Med (Lond). Published 7 October 2024. doi:10.
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