Perioperative medicine & outcomes

Association between baseline cerebral oxygenation and postoperative outcomes in older noncardiac surgical patients: An exploratory observational study

J Clin AnesthPublished Secondary analysis of a prospective observational cohort study

Authors' conclusion

The utility of baseline rSO2 as a biomarker of adverse postoperative outcomes can potentially extend to noncardiac surgical patients, especially for older populations.

Study context

Population
Patients over 65 years scheduled for elective noncardiac surgery, 2017–2019254 analysed
Comparison
Baseline rSO2 by 30-day readmission and mortality
Primary endpoint
Morbidity and mortality rates
Follow-up
30 days
Methodological detailsexploratory, Unilateral baseline rSO2 measured on admission to the surgical ward
  • Exploratory
  • Unilateral baseline rSO2 measured on admission to the surgical ward

Primary result

As reported in the abstract

30-day readmission and mortality; association with baseline rSO2
Readmitted within 30 days
17 (7 %)
Died within 30 days
5 (2 %)
Baseline rSO2 significantly associated with readmission, mean (SD) 58 (10) vs 65 (8)
P = 0.003
Baseline rSO2 significantly associated with mortality, mean (SD) 51 (15) vs 64 (8)
P < 0.001
Mortality prediction by baseline rSO2, AUC
0.801 (p = 0.021)

Original publication

Association between baseline cerebral oxygenation and postoperative outcomes in older noncardiac surgical patients: An exploratory observational study. J Clin Anesth. Published 4 March 2025. doi:10.1016/j.jclinane.2025.111806

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