Pain medicine

Association between chronic pain and risk of cardiometabolic multimorbidity: a prospective cohort study

Reg Anesth Pain MedPublished Prospective cohort study

Authors' conclusion

Our findings suggested that there was an elevated risk of cardiometabolic multimorbidity associated with an increased amount of chronic pain sites.

Study context

Population
Participants free of cardiometabolic multimorbidity at baselinemedian follow-up 13.7 years
Participants
452,818 participants
Exposure
Chronic pain by number of sites vs no chronic pain
Outcome
Cardiometabolic multimorbidity (≥2 of type 2 diabetes, ischaemic heart disease, stroke)

Main finding

As reported in the abstract

Cardiometabolic multimorbidity
Each group vs no chronic painHazard ratio (95% CI)
Four or more sites
1.82(1.61–2.06)
All over the body
1.59(1.30–1.93)
Developed cardiometabolic multimorbidity (all participants)
4445

Observational data: associations, not effects.

Further findings

Cardiometabolic multimorbidity, chronic pain in both head and stomach/abdomen

HR (95% CI)
Head and stomach/abdomen painHighest risk1.88 (1.60–2.20)

Original publication

Association between chronic pain and risk of cardiometabolic multimorbidity: a prospective cohort study. Reg Anesth Pain Med. Published 9 July 2024. doi:10.1136/rapm-2024-105486

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