Cardiothoracic & vascular anesthesia

Association Between Core Body Temperature at the Time of Separation From Cardiopulmonary Bypass and Postoperative Acute Kidney Injury: A Retrospective Observational Study

J Cardiothorac Vasc AnesthPublished Retrospective observational study

Authors' conclusion

Higher CPB separation temperature was independently associated with AKI.

Study context

Population
Adults undergoing cardiac surgery with cardiopulmonary bypass (CPB), university hospital, January 2022–February 2024
Participants
261 adults
Exposure
CPB separation temperature ≥36.2°C vs <36.2°C
Outcome
Postoperative AKI
Methodological detailssingle university hospital, multivariate logistic regression, propensity score matching
  • Single university hospital
  • Multivariate logistic regression
  • Propensity score matching

Main finding

As reported in the abstract

AKI incidence after propensity score matching

P = 0.014

Observational data: associations, not effects.

Further findings

Independent risk factors for AKI (multivariate analysis)

Higher BMI, OR
1.13; p = 0.009
Lower baseline hematocrit, OR
0.93; p = 0.031
Higher baseline serum creatinine, OR
1.14; p = 0.006
Longer CPB time, OR
1.13; p < 0.001
Higher CPB separation temperature, OR
1.13; p = 0.002

Optimal CPB separation temperature cutoff (ROC analysis)

Optimal cutoff
36.2°C

Original publication

Association Between Core Body Temperature at the Time of Separation From Cardiopulmonary Bypass and Postoperative Acute Kidney Injury: A Retrospective Observational Study. J Cardiothorac Vasc Anesth. Published 21 March 2026. doi:10.1053/j.jvca.2026.03.029

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