Cardiothoracic & vascular anesthesia
Association Between Intraoperative Landiolol Use and In-Hospital Mortality After Coronary Artery Bypass Grafting: A Nationwide Observational Study in Japan
Main findingResult — go to the resultOdds ratio 0.85 95% CI 0.78–0.94Authors' conclusion
Intraoperative landiolol use was associated with decreased in-hospital mortality in patients undergoing CABG.
Study context
- Population
- Patients undergoing coronary artery bypass grafting (CABG), Japanese Diagnosis Procedure Combination inpatient database, July 1, 2010–March 31, 2020
- Participants
- 118,506 patients · 24,893 matched pairs
- Exposure
- Intraoperative landiolol vs no landiolol
- Landiololn = 25,219
- Controln = 93,287reference
- Outcome
- In-hospital mortality
Methodological detailspropensity-score matched, nationwide database
- Propensity-score matched
- Nationwide database
Main finding
As reported in the abstract
Odds ratio
0.85
95% CI 0.78–0.94
P = 0.010
By group
Landiolol vs Control
OR 0.85 (95% CI 0.78–0.94); P = 0.010
Observational data: associations, not effects.
Original publication
Association Between Intraoperative Landiolol Use and In-Hospital Mortality After Coronary Artery Bypass Grafting: A Nationwide Observational Study in Japan. Anesth Analg. Published 18 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →