Respiratory failure & ventilation
The Association Between Mechanical Power Within the First 24 Hours and ICU Mortality in Mechanically Ventilated Adult Patients With Acute Hypoxemic Respiratory Failure: A Registry-Based Cohort Study
Main finding · ICU mortalityResult — go to the resultOdds ratio 1.58 95% CI 1.44–1.72Authors' conclusion
In this study, exposure to high MP within the first 24 hours of IMV was associated with increased ICU mortality in patients with AHRF.
Study context
- Population
- Adults with acute hypoxemic respiratory failure (AHRF) receiving invasive mechanical ventilation (IMV); excluded if IMV > 24 hours before inclusion or receiving extracorporeal life supportof 21,714 in registry
- Participants
- 9,031 adults
- Exposure
- High mechanical power (MP) vs lower MP within the first 24 hours of IMV
- Outcome
- ICU mortality
Methodological detailsinverse probability of treatment weighting, change-point regression with restricted cubic splines
- Inverse probability of treatment weighting
- Change-point regression with restricted cubic splines
Main finding
As reported in the abstract
Odds ratio
1.58
95% CI 1.44–1.72
High MP vs Low MP
OR 1.58 (95% CI 1.44–1.72)
Observational data: associations, not effects.
Further findings
- High MP associated with lower extubation rates and fewer ventilator-free days
Original publication
The Association Between Mechanical Power Within the First 24 Hours and ICU Mortality in Mechanically Ventilated Adult Patients With Acute Hypoxemic Respiratory Failure: A Registry-Based Cohort Study. Chest. Published 28 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →