Neuroanesthesia & neurocritical care
Association Between Severe Anaemia and Outcome in Moderate and Severe Traumatic Brain Injury: A Retrospective Cohort Study
Main finding · Unfavourable functional outcome (GOS 1 to 3)Result — go to the resultOdds ratio 4.06 95% CI 1.54–10.72Authors' conclusion
Among patients with moderate to severe TBI, severe anaemia with an Hb level below 100 g/L during hospitalisation was independently associated with unfavourable functional outcome at hospital discharge.
Study context
- Population
- Successive patients admitted to Tampere University Hospital's ED with moderate to severe traumatic brain injury (TBI), August 2010 to July 2012severe anaemia in 45.5%
- Participants
- 145 patients
- Exposure
- Severe anaemia vs no severe anaemia
- Outcome
- Glasgow Outcome Scale, dichotomized as poor (Glasgow Outcome Scale (GOS) 1 to 3) and good (GOS 4 to 5) outcome
- Follow-up
- Hospital discharge
Methodological detailssingle-centre
- Single-centre
Main finding
Unfavourable functional outcome (GOS 1 to 3)
Odds ratio
4.06
95% CI 1.54–10.72
P = 0.005
By group
Severe anaemia vs No severe anaemia
OR 4.06 (95% CI 1.54–10.72); P = 0.005
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
Mortality · 3 months · univariate analysis
P = 0.028
Mortality · 6 months · univariate analysis
P = 0.048
Mortality · 12 months · univariate analysis
P = 0.011
Long-term mortality (multivariable analysis)
- Severe anaemia not independently associated with higher long-term mortality
Original publication
Association Between Severe Anaemia and Outcome in Moderate and Severe Traumatic Brain Injury: A Retrospective Cohort Study. Acta Anaesthesiol Scand. Published 13 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →