Cardiothoracic & vascular anesthesia

Association of Low Skeletal Muscle Mass and Low Skeletal Muscle Radiodensity With Postoperative Delirium in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting: A Retrospective Cohort Study

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

Among patients undergoing OPCABG, low SMI and low SMD were independently connected to POD. Additionally, the highest risk of POD was observed in patients with both low SMI and low SMD.

Study context

Population
Adults undergoing off-pump CABG (off-pump coronary artery bypass grafting (OPCABG)), university-affiliated hospital, January–December 2021
Participants
228 adults
Exposure
Low vs higher skeletal muscle index (SMI) and radiodensity (SMD) on preoperative CT at L3
Outcome
POD
Methodological detailssingle-center, retrospective observational, Low SMI/SMD = lowest sex-specific tertile
  • Single-center
  • Retrospective observational
  • Low SMI/SMD = lowest sex-specific tertile

Main finding

As reported in the abstract

Multivariable regression; independent predictor
Odds ratio (95% CI)
SMI (continuous)
0.95(0.90–0.999)
SMD (continuous)
0.93(0.87–0.99)
Patients who developed postoperative delirium (POD)
54 (23.7%)

Observational data: associations, not effects.

Further findings

POD, concomitant low SMI and low SMD (subgroup)

OR (95% CI)
Low SMI and low SMDBroad CI likely reflects limited number of patients3.83 (1.35–10.84)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Association of Low Skeletal Muscle Mass and Low Skeletal Muscle Radiodensity With Postoperative Delirium in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting: A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 24 July 2026. doi:10.1053/j.jvca.2026.07.041

Composed by AI from the published abstract and checked against it. How Briefs are made →

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