Haemodynamics, fluids & transfusion
Associations between reduction of hypotension and treatment intensity in hypotension prediction index studies
Authors' conclusion
Across randomized HPI trials, reduced hypotension was frequently accompanied by increased treatment intensity.
Study context
- Population
- Randomized trials evaluating Hypotension Prediction Index (HPI)-guided hypotension prevention
- Participants
- 2,342 participants · 20 RCTs
- Comparison
- Hypotension reduced vs Hypotension not reduced
- Hypotension reducedn = 13
- Hypotension not reducedn = fivereference
- Outcome
- Association between significant reduction in the primary hypotension outcome and significant increase in any hemodynamic treatment (fluids, vasopressors, or inotropes) in the HPI group
Methodological details2×2 tabulation, Fisher's exact test, correlation analysis
- 2×2 tabulation
- Fisher's exact test
- Correlation analysis
Pooled result
As reported in the abstract
Significantly greater treatment intensity in HPI group
Hypotension reduced
69%
9 of 13
Hypotension not reduced
0
events
P = 0.029
Further pooled results
Time-weighted average (TWA) of mean arterial pressure (MAP)< 65 mmHg difference vs treatment intensity category
- TWA differences significantly correlated with treatment intensity
- P < 0.001
Original publication
Associations between reduction of hypotension and treatment intensity in hypotension prediction index studies. Anesthesiology. Published 9 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →