Perioperative medicine & outcomes
Associations of Intraoperative Hypotension and Perioperative Blood Pressure with Delirium after Noncardiac Surgery: A Retrospective Cohort Analysis
Main finding · Postoperative delirium vs intraoperative AUC of MAP <65 mmHgResult — go to the resultOdds ratio 1.000 95% CI 0.999–1.000Authors' conclusion
Intraoperative hypotension and intraoperative average blood pressure were not associated with postoperative delirium. Postoperative higher average blood pressures demonstrated a statistically significant association with delirium; however, this finding lacks clinical relevance.
Study context
- Population
- Adult noncardiac surgery patients, single academic center, 2018–2022
- Participants
- 38,940 noncardiac surgeries
- Exposure
- Intraoperative hypotension (AUC of intraoperative mean arterial pressure (MAP) <65 mmHg) and perioperative time-weighted average MAP vs postoperative delirium
- Outcome
- Postoperative delirium vs intraoperative AUC of MAP <65 mmHg
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Odds ratio
1.000
95% CI 0.999–1.000
P = 0.17
Intraoperative hypotension (AUC of intraoperative MAP <65 mmHg) and perioperative time-weighted average MAP vs postoperative delirium
OR 1.000 (95% CI 0.999–1.000); P = 0.17
- Incidence of postoperative delirium (overall)
- 6.56%
Observational data: associations, not effects.
Further findings
Intraoperative time-weighted average MAP
| OR (95% CI) | P value | ||
|---|---|---|---|
| Intraoperative time-weighted average MAP (increasing) | 0.993 (0.990–0.996) | P < 0.001 | |
| 0.512Odds ratio (log scale) |
- Intraoperative time-weighted average MAP: linear association; increasing MAP associated with lower delirium risk
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Associations of Intraoperative Hypotension and Perioperative Blood Pressure with Delirium after Noncardiac Surgery: A Retrospective Cohort Analysis. Anesthesiology. Published 16 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →