Cardiothoracic & vascular anesthesia
Balanced Nonopioid General Anesthesia With Lidocaine Is Associated With Lower Postoperative Complications Compared With Balanced Opioid General Anesthesia With Sufentanil for Cardiac Surgery With Cardiopulmonary Bypass: A Propensity Matched Cohort Study
Authors' conclusion
A balanced nonopioid general anesthesia protocol with lidocaine was associated with lower odds of postoperative complication composite outcome based on respiratory failure and confusion.
Study context
- Population
- Patients undergoing cardiac surgery with CPB, 2019–2021, excluding heart transplantation, left ventricular assistance device and off-pump surgery772 matched per group
- Participants
- 772 vs 772
- Exposure
- Nonopioid vs Opioid
- Nonopioidn = 772
- Opioidn = 772reference
- Outcome
- Collapsed composite of postoperative complications (respiratory failure and confusion)
Methodological detailspropensity-score matched
- Propensity-score matched
Main finding
Postoperative composite complications
Odds ratio
0.72
95% CI 0.58–0.92
P = 0.027
Events by group
Nonopioid vs Opioid
OR 0.72 (95% CI 0.58–0.92); P = 0.027
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
AKI, death and hospital LOS
- Did not differ between the 2 groups
Original publication
Balanced Nonopioid General Anesthesia With Lidocaine Is Associated With Lower Postoperative Complications Compared With Balanced Opioid General Anesthesia With Sufentanil for Cardiac Surgery With Cardiopulmonary Bypass: A Propensity Matched Cohort Study. Anesth Analg. Published 10 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →