Cardiothoracic & vascular anesthesia
Blood Culture Positivity and Clinical Correlates of Bloodstream Infections in Post-cardiac Surgery Patients
Authors' conclusion
In a single-center cohort of cardiac surgical patients, end-stage renal disease, tachycardia, recent mechanical ventilation, severe thrombocytopenia, and total parental nutrition were associated with BSI. Leukocytosis and fever were not found to be associated with culture-positive BSI.
Study context
- Population
- Post-cardiac surgery ICU patients with blood cultures obtained, July 1, 2018–June 30, 20231,294 cultures
- Participants
- 533 patients
- Outcome
- BSI-positive cultures; independent associations with BSI
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Cultures demonstrating bloodstream infection (BSI), 115 of 1,294
- 8.9%
- Total parental nutrition in prior 48 h, OR
- 5.44 (95% CI 2.07, 14.30)
- Severe thrombocytopenia, OR
- 3.75 (95% CI 1.75, 8.04)
- End-stage renal disease, OR
- 2.19 (95% CI 1.01, 4.78)
- Mechanical ventilation in prior 48 h, OR
- 1.92 (95% CI 1.10, 3.36)
- Heart rate >100 in prior 24 h, OR
- 1.70 (95% CI 1.03, 2.79)
Observational data: associations, not effects.
Further findings
Blood cultures performed among cardiac surgery patients
- Patients with blood cultures, 533 of 3,095
- 17.2%
- Median day of culture acquisition, POD
- 13
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Blood Culture Positivity and Clinical Correlates of Bloodstream Infections in Post-cardiac Surgery Patients. J Cardiothorac Vasc Anesth. Published 3 July 2025. doi:10.
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