Pediatric anesthesia & critical care

Brief report: incidence and outcomes of pediatric tracheal intubation-associated cardiac arrests in the ICU-RESUS clinical trial

Crit CarePublished Secondary analysis of the ICU-RESUS randomised trial

Authors' conclusion

While duration of CPR was longer in TI-CA patients, there were no differences in unadjusted outcomes following TI-CA versus non-TI-CA.

Study context

Population
Children with cardiac arrest in the PICU (ICU-RESUS trial and CPR-NOVA study)48 (15.2%) TI-CA
Participants
315 children
Comparison
Tracheal intubation (TI)-associated cardiac arrest vs non-TI-CA
  • TI-CAn = 48
  • non-TI-CAn = 267reference
Primary endpoint
Survival to hospital discharge with favorable neurological outcome:
  • Pediatric Cerebral Performance Category score 1-3
  • Unchanged
Methodological detailsancillary CPR-NOVA study
  • Ancillary CPR-NOVA study

Primary result

As reported in the abstract

P = 0.53

Further findings

Duration of CPR

P = 0.03

ROSC

P = 0.73

Pre-arrest NIV

TI-CA occurring within 20 min after intubation (not during)
48% · 23 of 48

Pre-existing medical conditions

Similar between groups

Original publication

Brief report: incidence and outcomes of pediatric tracheal intubation-associated cardiac arrests in the ICU-RESUS clinical trial. Crit Care. Published 30 August 2024. doi:10.1186/s13054-024-05065-0

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