Pediatric anesthesia & critical care
Brief report: incidence and outcomes of pediatric tracheal intubation-associated cardiac arrests in the ICU-RESUS clinical trial
Authors' conclusion
While duration of CPR was longer in TI-CA patients, there were no differences in unadjusted outcomes following TI-CA versus non-TI-CA.
Study context
- Population
- Children with cardiac arrest in the PICU (ICU-RESUS trial and CPR-NOVA study)48 (15.2%) TI-CA
- Participants
- 315 children
- Comparison
- Tracheal intubation (TI)-associated cardiac arrest vs non-TI-CA
- TI-CAn = 48
- non-TI-CAn = 267reference
- Primary endpoint
- Survival to hospital discharge with favorable neurological outcome:
- Pediatric Cerebral Performance Category score 1-3
- Unchanged
Methodological detailsancillary CPR-NOVA study
- Ancillary CPR-NOVA study
Primary result
As reported in the abstract
P = 0.53
Further findings
Duration of CPR
P = 0.03
ROSC
P = 0.73
Pre-arrest NIV
- TI-CA occurring within 20 min after intubation (not during)
- 48% · 23 of 48
Pre-existing medical conditions
- Similar between groups
Original publication
Brief report: incidence and outcomes of pediatric tracheal intubation-associated cardiac arrests in the ICU-RESUS clinical trial. Crit Care. Published 30 August 2024. doi:10. 1186/ s13054-024-05065-0
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