Cardiac arrest & resuscitation
The association of arterial blood pressure waveform-derived area duty cycle with intra-arrest hemodynamics and cardiac arrest outcomes
Authors' conclusion
In this multicenter cohort, a lower ABP-ADC was associated with higher sBPs during CPR.
Study context
- Population
- Paediatric in-hospital CPR events with invasive arterial waveform data (ICU-RESUS trial)of 1129 CPR events
- Participants
- 273 events
- Comparison
- ABP-ADC groups
- Primary endpoint
- SBP
Methodological detailsretrospective, prospectively collected data, multicenter
- Retrospective
- Prospectively collected data
- Multicenter
Primary result
As reported in the abstract
- Higher ABP-ADC associated with lower SBP (univariable)
- p < 0.01
- Higher ABP-ADC associated with failing to achieve SBP targets (univariable)
- p < 0.01
Secondary outcomes
| Outcome | Point estimate (mmHg) (95% CI) | P value |
|---|---|---|
| SBP, ABP-ADC <33% vs ≥33% (exploratory multivariable) | 13.18 (5.30–21.07) | P < 0.01 |
- SBP, ABP-ADC <33% vs ≥33% (exploratory multivariable): higher SBP; cut point 33% by spline/ROC and clinical judgement
Other intra-arrest physiologic parameters, CPR quality metrics, patient outcomes
- Similar across ABP-ADC groups
SBP, ABP-ADC <33% vs ≥33% (exploratory multivariable)
- Other intra-arrest physiologic and patient outcomes similar
Original publication
The association of arterial blood pressure waveform-derived area duty cycle with intra-arrest hemodynamics and cardiac arrest outcomes. Resuscitation. Published 25 August 2023. doi:10.
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