Cardiothoracic & vascular anesthesia

Can near infrared spectroscopy (NIRS) be a surrogate indicator of elective shunt in carotid endarterectomy? A single-center observational retrospective study says no

J Clin Monit ComputPublished Retrospective observational diagnostic accuracy study

Authors' conclusion

NIRS is inferior to multimodality IONM in detecting brain ischemia and predicting postoperative neurological status during CEA under general anesthesia.

Study context

Population
Consecutive patients undergoing carotid endarterectomy under GA
Participants
86 consecutive patients
Comparison
NIRS vs multimodality intraoperative neuromonitoring
Outcome
Detection of brain ischemia (indication of elective shunt) and prediction of postoperative neurological status: sensitivity, specificity, PPV, NPV
Methodological detailssingle-centre, consecutive patients
  • Single-centre
  • Consecutive patients

Performance

As reported in the abstract

Detection of brain ischemia
Test or modelSensitivitySpecificityPPVNPV
NIRS77.7%89.6%46.6%97.2%
Multimodality intraoperative neuromonitoring (IONM)100%100%100%100%

Sensitivity

NIRS77.7%
Multimodality intraoperative neuromonitoring (IONM)100%

Specificity

NIRS89.6%
Multimodality intraoperative neuromonitoring (IONM)100%

PPV

NIRS46.6%
Multimodality intraoperative neuromonitoring (IONM)100%

NPV

NIRS97.2%
Multimodality intraoperative neuromonitoring (IONM)100%

Further findings

OutcomeValues
Prediction of postoperative outcome, EEG alone (within multimodality IONM)EEG PPV 100% · NPV 100%

Prediction of postoperative outcome, EEG alone (within multimodality IONM)

EEG showed the best results among IONM methods

Demographic or clinical data, true-positive vs false-positive patients

No significant difference

Original publication

Can NIRS be a surrogate indicator of elective shunt in carotid endarterectomy? A single-center observational retrospective study says no. J Clin Monit Comput. Published 8 December 2023. doi:10.1007/s10877-023-01114-1

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