Organ support & nutrition

Cannula-Associated Deep Vein Thrombosis After Venovenous Extracorporeal Membrane Oxygenation in Patients with and Without Systemic Anticoagulation

J Cardiothorac Vasc AnesthPublished Retrospective observational study

Authors' conclusion

This study showed a high incidence of cannula-related venous thrombosis after VV-ECMO decannulation. Surprisingly, the incidence of CaDVT in anticoagulation-free patients was the same as in patients requiring anticoagulation. Anticoagulated patients required longer support on VV-ECMO and required more transfusions.

Study context

Population
Consecutive patients successfully decannulated from VV-ECMO for refractory ARDS, 2017–2022; COVID-19 patients excluded94 weaned
Participants
161 participants
Exposure
Systemic anticoagulation vs no anticoagulation during VV-ECMO
  • No anticoagulation (AC)n = 52reference
  • ACn = 23
Outcome
Cannula-associated thrombus
Follow-up
After decannulation
Methodological detailssingle-centre, tertiary academic medical center, consecutive patients
  • Single-centre
  • Tertiary academic medical center
  • Consecutive patients

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

Blood products and duration of VV-ECMO support

AC patients required more blood products during the ECMO run and longer VV-ECMO support

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Cannula-Associated Deep Vein Thrombosis After Venovenous Extracorporeal Membrane Oxygenation in Patients with and Without Systemic Anticoagulation. J Cardiothorac Vasc Anesth. Published 15 September 2023. doi:10.1053/j.jvca.2023.09.009

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