Cardiothoracic & vascular anesthesia
Capnodynamic monitoring of lung volume and pulmonary blood flow during alveolar recruitment: a prospective observational study in postoperative cardiac patients
Authors' conclusion
Capnodynamic monitoring of end-expiratory lung volume and effective pulmonary blood flow early in postoperative cardiac patients identified a characteristic parallel increase in both lung volume and perfusion after the recruitment manoeuvre in patients with a significant increase in oxygen delivery.
Study context
- Population
- Postoperative cardiac surgery patients undergoing alveolar recruitment (incremental positive end-expiratory pressure (PEEP) from 5 to max 15 cmH2O over 30 min)
- Participants
- 64 patients
- Exposure
- Responders vs non-responders after alveolar recruitment
- Respondersn = 27
- Outcome
- Change in end-expiratory lung volume and effective pulmonary blood flow after recruitment, responders vs non-responders
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Correlation of increased end-expiratory lung volume and effective pulmonary blood flow (responders only)
- Positive correlation, r (95% CI 0.5-0.90, p < 0.001), only observed in responders
- 0.79
Correlation of change in oxygen delivery index with change in end-expiratory lung volume
- R
- 0.39 (95% CI 0.16-0.59, p = 0.002)
Correlation of change in oxygen delivery index with change in effective pulmonary blood flow
- R
- 0.60 (95% CI 0.41-0.74, p < 0.001)
Original publication
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