Cardiothoracic & vascular anesthesia
Cardiac surgery-associated acute kidney injury requiring haemofiltration: The immediate postoperative phase is critical to achieve equivalent long-term survival
Authors' conclusion
Postoperative AKI requiring haemofiltration is associated with poor outcomes following cardiac surgery. However, in patients surviving the acute postoperative phase, there was no significant difference in long-term survival compared to those who did not require haemofiltration.
Study context
- Population
- Adults undergoing cardiac surgery 2015–2024, excluding preoperative RRTbefore matching
- Participants
- 16,681 adults
- Exposure
- Group H vs Group C
- Group Hn = 510
- Group Cn = 1,020reference
- Outcome
- Hospital mortality
Methodological details1:2 propensity-score matched, single-centre
- 1:2 propensity-score matched
- Single-centre
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Long-term survival, up to 5 years | 1.81 (1.50–2.18) | P < 0.001 | |
| 0.512Hazard ratio (log scale) |
Long-term survival, up to 5 years
- Higher mortality up to five years in Group H
Long-term survival among patients surviving past hospital discharge (conditional survival analysis)
- Long-term survival comparable between groups (HR)
- 1.23
- 95% CI
- 0.95-1.58
- P
- P = 0.115
- Conditional survival analysis
Original publication
Cardiac surgery-associated acute kidney injury requiring haemofiltration: The immediate postoperative phase is critical to achieve equivalent long-term survival. J Crit Care. Published 1 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →