Cardiac arrest & resuscitation
Cerebral blood flow estimation using near-infrared spectroscopy (NIRS) in cardiac arrest patients: correlation with return of spontaneous circulation (ROSC) outcomes
Authors' conclusion
The relationship between MAP and CBF during CPR varies by pressure range, with a positive correlation emerging at mean arterial pressure ≥60 mmHg, specifically among patients with better short-term outcomes.
Study context
- Population
- Adults (≥18 years) with out-of-hospital cardiac arrest (OHCA) undergoing cardiopulmonary resuscitation (CPR) with invasive arterial monitoring and NIRSanalysed
- Participants
- 74 adults
- Exposure
- ROSC vs non-ROSC patients: Mean arterial pressure (MAP)–cerebral blood flow (CBF) relationship during CPR
- Outcome
- Relationship of NIRS-estimated CBF to MAP (20 mmHg intervals: 0-20, 20-40, 40-60, 60-80 mmHg) during CPR
Main finding
As reported in the abstract
MAP–CBF correlation by MAP range
- Significant positive MAP–CBF correlation in the 60-80 mmHg range in ROSC patients
- p < 0.001
Observational data: associations, not effects.
Original publication
Cerebral blood flow estimation using NIRS in cardiac arrest patients: correlation with ROSC outcomes. Resuscitation. Published 29 January 2026. doi:10.
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