ICU sedation, delirium & recovery
Characteristics, outcomes, and complications among nonagenarian and centenarian patients admitted to the intensive care unit: a scoping review
An erratum to this article was published (Crit Care, 20 Aug 2025 ↗)
Authors' conclusion
Nonagenarians and centenarians admitted to ICU are a highly comorbid and vulnerable population who experience prolonged hospital stays and complications. However four out of five survive to hospital discharge and half are alive at one year after admission.
Study context
- Population
- Nonagenarians and centenarians admitted to ICU
- Participants
- 16,859 participants · 36 studies
- Outcome
- Hospital mortality
Methodological detailsmostly retrospective studies
- Mostly retrospective studies
Main finding
As reported in the abstract
Median hospital mortality (range 0%-62.5%; IQR 15%-35.5%)
25.55%
Observational data: associations, not effects.
Further findings
Patient characteristics
- Mean age (years)
- 92.4
- Male prevalence
- 39.3%
- Multiple comorbidities present in the majority of patients
Mechanical ventilation
- Overall received mechanical ventilation
- 40.7%
- Median across studies (range 0%-100%; IQR 23.8%-50%)
- 36%
- Mean duration (h)
- 90.4
- Median duration, h (range 10-221 h; IQR 12.25-146.5 h)
- 84
ICU LOS
- Mean ICU stay (days)
- 5.4
- Median ICU stay, days (range 0.9-13 days; IQR 2.55-7.03 days)
- 5
Hospital LOS
- Median hospital stay, days (range 5.7-31 days; IQR 11-17.6 days)
- 12.4
Long-term mortality
- Mean 6-month mortality
- 38.6%
- Mean 1-year mortality
- 45.6%
Safety
- Cardiovascular and renal complications were common
Original publication
Characteristics, outcomes, and complications among nonagenarian and centenarian patients admitted to the intensive care unit: a scoping review. Crit Care. Published 13 March 2025. doi:10.
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