Hemodynamics, fluids & transfusion
Circulating biomarkers of vasoplegia: a systematic review
Authors' conclusion
The lack of standardisation in biomarker assay methods and vasoplegia definitions remains a significant barrier to comparative analysis.
Study context
- Population
- Adults in critical care or perioperative settings with vasoplegia (reduced vascular resistance and hypotension requiring vasopressors)43 studies
- Outcome
- Circulating biomarkers associated with incidence, severity, prediction and progression of vasoplegia
Methodological detailsPRISMA 2020, no meta-analysis (heterogeneity)
- PRISMA 2020
- No meta-analysis (heterogeneity)
Pooled result
As reported in the abstract
Unique biomarkers examined
39
Original publication
Circulating biomarkers of vasoplegia: a systematic review. Ann Intensive Care. Published 30 September 2025. doi:10.
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