Clinical impact of screening computed tomography in extracorporeal membrane oxygenation: a retrospective cohort study
Authors' conclusion
Screening CT frequently identifies extrapulmonary findings of clinical significance. Newly detected intracranial haemorrhage, cerebral infarction and colitis were associated with increased ICU mortality.
Study context
- Population
- Consecutive patients on initiation of V–V ECMO undergoing admission screening computed tomography (CT) (head, abdomen and pelvis with contrast), 2011–2021761 underwent CT
- Participants
- 833 patients
- Outcome
- Prevalence of extrapulmonary findings on screening CT following V-V ECMO initiation
Methodological detailsconsecutive patients, multivariable logistic regression
- Consecutive patients
- Multivariable logistic regression
Main finding
As reported in the abstract
Incidental extrapulmonary finding on screening CT
Incidental extrapulmonary finding
227 patients
29.8%
Leading to an invasive procedure
12 of 227
5.3%
Change in medical management (mainly anticoagulation strategy)
119 of 227
52.4%
Observational data: associations, not effects.
Further findings
Extrapulmonary findings associated with ECMO ICU mortality
| OR (95% CI) | ||
|---|---|---|
| Intracranial haemorrhage | 2.34 (1.31–4.12) | |
| Cerebral infarction | 3.59 (1.26–9.86) | |
| Colitis | 2.80 (1.35–5.67) | |
| 0.10.31310Odds ratio (log scale) |
ECMO ICU LOS and ICU mortality
- ECMO ICU LOS, days (IQR 12-23)
- 19
- ICU mortality at the ECMO centre
- 18.9%
Original publication
Clinical impact of screening computed tomography in extracorporeal membrane oxygenation: a retrospective cohort study. Ann Intensive Care. Published 26 September 2023. doi:10.
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