Sepsis & infection

Coagulopathy in Critically Ill Patients With Sepsis: Protocol for a Scoping Review

Acta Anaesthesiol ScandPublished Scoping review protocol

Study context

Population
Adults (≥ 18 years) with sepsis and coagulopathy or disseminated intravascular coagulation (DIC); original clinical research of any design published from 1 January 1996 onwards, in English
Methodological detailsduplicate screening and data extraction, critical appraisal of included studies, Searches in PubMed, EMBASE, Web of Science and CENTRAL, plus reference list screening, Two reviewers screen independently and extract data in duplicate using a piloted form; a third senior reviewer adjudicates disagreements, Data: study characteristics, population, diagnostic approaches, frequency of coagulopathy, management, clinical outcomes, hospital settings and geographical origin; descriptive statistics, tables and narrative summaries
  • Duplicate screening and data extraction
  • Critical appraisal of included studies
  • Searches in PubMed, EMBASE, Web of Science and CENTRAL, plus reference list screening
  • Two reviewers screen independently and extract data in duplicate using a piloted form; a third senior reviewer adjudicates disagreements
  • Data: study characteristics, population, diagnostic approaches, frequency of coagulopathy, management, clinical outcomes, hospital settings and geographical origin; descriptive statistics, tables and narrative summaries

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Coagulopathy in Critically Ill Patients With Sepsis: Protocol for a Scoping Review. Acta Anaesthesiol Scand. Published 5 August 2026. doi:10.1111/aas.70303

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