Pain medicine

Comparing modalities of opioid education in patients undergoing total knee arthroplasty: a randomized pilot trial

Reg Anesth Pain MedPublished Randomised controlled trial

Authors' conclusion

There were no statistically significant differences in outcomes of NRS pain scores or opioid usage among groups suggesting that educational interventions were similarly effective.

Study context

Population
Patients undergoing total knee arthroplasty (TKA)
Participants
42 patients
Comparison
In-person or video opioid education vs webinar
Primary endpoint
Number of opioid refill requests
Follow-up
Through POD 30 and POD 60
Methodological detailspilot, prospective, three-arm, Pilot trial demonstrated successful recruitment and retention; likely underpowered to detect a difference
  • Pilot
  • Prospective
  • Three-arm
  • Pilot trial demonstrated successful recruitment and retention; likely underpowered to detect a difference

Primary result

As reported in the abstract

Opioid refill requests · POD 30 and POD 60
Refill requests ranged from 0% to 16.7% at postoperative day (POD) 30 (Fisher's exact test)
p=0.625
Refill requests ranged from 0% to 8.3% at POD 60
p=1.000

Secondary outcomes

OutcomeWebinarIn-personVideoP value
Opioid refill requests, POD 21 to 60 (median, per group)Across three groupsmedian 0 (IQR 0.0–0.0) requestsmedian 0 (IQR 0.0–0.0) requestsmedian 0 (IQR 0.0–0.0) requestsP = 0.381

Average Numerical Rating Scale (NRS) pain score · POD 1, 7 and 14

No significant differences among groups at any time point; average NRS 5 or below for all groups on POD 1, 7 and 14

Opioid consumption (oral morphine equivalents (OME))

No significant differences among groups at any time point; by POD 7 all groups average daily OME 14 or below

Original publication

Comparing modalities of opioid education in patients undergoing total knee arthroplasty: a randomized pilot trial. Reg Anesth Pain Med. Published 26 September 2024. doi:10.1136/rapm-2024-105701

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