Comparing modalities of opioid education in patients undergoing total knee arthroplasty: a randomized pilot trial
Authors' conclusion
There were no statistically significant differences in outcomes of NRS pain scores or opioid usage among groups suggesting that educational interventions were similarly effective.
Study context
- Population
- Patients undergoing total knee arthroplasty (TKA)
- Participants
- 42 patients
- Comparison
- In-person or video opioid education vs webinar
- Primary endpoint
- Number of opioid refill requests
- Follow-up
- Through POD 30 and POD 60
Methodological detailspilot, prospective, three-arm, Pilot trial demonstrated successful recruitment and retention; likely underpowered to detect a difference
- Pilot
- Prospective
- Three-arm
- Pilot trial demonstrated successful recruitment and retention; likely underpowered to detect a difference
Primary result
As reported in the abstract
Opioid refill requests · POD 30 and POD 60
- Refill requests ranged from 0% to 16.7% at postoperative day (POD) 30 (Fisher's exact test)
- p=0.625
- Refill requests ranged from 0% to 8.3% at POD 60
- p=1.000
Secondary outcomes
| Outcome | Webinar | In-person | Video | P value |
|---|---|---|---|---|
| Opioid refill requests, POD 21 to 60 (median, per group)Across three groups | median 0 (IQR 0.0–0.0) requests | median 0 (IQR 0.0–0.0) requests | median 0 (IQR 0.0–0.0) requests | P = 0.381 |
Average Numerical Rating Scale (NRS) pain score · POD 1, 7 and 14
- No significant differences among groups at any time point; average NRS 5 or below for all groups on POD 1, 7 and 14
Opioid consumption (oral morphine equivalents (OME))
- No significant differences among groups at any time point; by POD 7 all groups average daily OME 14 or below
Original publication
Comparing modalities of opioid education in patients undergoing total knee arthroplasty: a randomized pilot trial. Reg Anesth Pain Med. Published 26 September 2024. doi:10. 1136/ rapm-2024-105701
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