Comparing oxygen therapies for hypoxemia prevention during gastrointestinal endoscopy under procedural sedation: A systematic review and network meta-analysis
Authors' conclusion
During gastrointestinal endoscopy under procedural sedation, all other advanced oxygen therapies were found to be more efficacious than nasal cannula. NIPPV and WNJT appear to be the most efficacious oxygen therapy for preventing hypoxemia.
Study context
- Population
- Adults (≥18 years) undergoing gastrointestinal endoscopy under procedural sedation
- Participants
- 7,552 adults · 27 randomized clinical trials (RCTs)
- Comparison
- Oxygen therapies vs NC
- Outcome
- Incidence of hypoxemia (SpO2)
Methodological detailsrandom-effects, Risk of bias by Cochrane guidance; evidence quality by Grading of Recommendations Assessment, Development and Evaluation (GRADE)
- Random-effects
- Risk of bias by Cochrane guidance; evidence quality by GRADE
Pooled result
As reported in the abstract
Each group vs NCOdds ratio (95% CI)
NIPPV95% PrI: 0.06-0.41
0.16(0.08–0.31)
WNJT95% PrI: 0.07-0.42
0.17(0.10–0.30)
Original publication
Comparing oxygen therapies for hypoxemia prevention during gastrointestinal endoscopy under procedural sedation: A systematic review and network meta-analysis. J Clin Anesth. Published 17 August 2024. doi:10.
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