Anesthetic drugs & techniques

Effect of supraglottic jet oxygenation and ventilation on hypoxemia in patients undergoing endoscopic surgery with sedation: A meta-analysis of randomized controlled trials

J Clin AnesthPublished Systematic review and meta-analysis of randomised trials

Pooled resultResult — go to the resultRelative risk 0.18 95% CI 0.11–0.28

Authors' conclusion

Compared with the COT, the SJOV decreased the incidence of hypoxemia in high-risk patients during endoscopic surgery with sedation. There was an increased risk of dry mouth, but not of nose bleeding or sore throat, during endoscopic surgery under sedation.

Study context

Population
Patients undergoing endoscopic surgery with sedation
Participants
2,017 patients · 9 trials
Comparison
Supraglottic jet oxygenation and ventilation (SJOV) vs conventional oxygen therapy
Outcome
Incidence of hypoxemia
Methodological detailssubgroup analyses
  • Subgroup analyses

Pooled result

As reported in the abstract

Relative risk

0.18

95% CI 0.11–0.28

SJOV vs COT
RR 0.18 (95% CI 0.11–0.28)

Further pooled results

Hypoxemia by risk (subgroup)

SJOV reduced hypoxemia in the high-risk group but had no effect on the low-risk group

Respiratory depression

Lower incidence with SJOV than conventional oxygen therapy (COT)

Original publication

Effect of supraglottic jet oxygenation and ventilation on hypoxemia in patients undergoing endoscopic surgery with sedation: A meta-analysis of randomized controlled trials. J Clin Anesth. Published 23 July 2024. doi:10.1016/j.jclinane.2024.111559

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