Nasal continuous positive pressure versus simple face mask oxygenation for adult obese and obstructive sleep apnea patients undergoing colonoscopy under propofol-based general anesthesia without tracheal intubation: A randomized controlled trial
An erratum to this article was published (J Clin Anesth, Oct 2024 ↗)
Authors' conclusion
A nasal CPAP did not prevent hypoxemia and should not be used routinely for colonoscopy in obese or OSA patients if a simple face mask is an alternative therapy.
Study context
- Population
- Obese and/or OSA adults undergoing colonoscopy under propofol GA without planned tracheal intubation, tertiary academic centre6 had a hypoxemic event
- Participants
- 109 adults
- Comparison
- Nasal CPAP mask vs simple face mask for supplementary O2 at 10 L/min
- Nasal CPAPn = 55
- Simple face maskn = 54reference
- Primary endpoint
- Difference in mean percentage of time with oxygen saturation below 90%
Methodological detailssingle-centre, prospective
- Single-centre
- Prospective
Primary result
As reported in the abstract
Percentage of time with oxygen saturation below 90%
- Difference not clinically relevant among patients with a hypoxemic event
- Nasal CPAP vs Simple face mask: P = 1.0
Secondary outcomes
Chin lift required
P = 0.01
Oral cannula insertion
P = 0.03
At least one airway maneuver
P = 0.005
| Outcome | Nasal CPAP | Simple face mask | P value |
|---|---|---|---|
| Patient tolerance to device scoreLower in the nasal CPAP group | 8.85 | 9.56 | P = 0.003 |
Original publication
Nasal continuous positive pressure versus simple face mask oxygenation for adult obese and obstructive sleep apnea patients undergoing colonoscopy under propofol-based general anesthesia without tracheal intubation: A randomized controlled trial. J Clin Anesth. Published 3 July 2023. doi:10.
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