Perioperative medicine & outcomes
Comparing perioperative outcomes between regional anesthesia and general anesthesia in patients undergoing hip fracture surgery: a systematic review and meta-analysis
Pooled result · 30-day mortalityResult — go to the resultOdds ratio 0.88 95% CI 0.44–1.74Authors' conclusion
In this updated systematic review and meta-analysis, RA did not reduce postoperative 30-day mortality in hip fracture surgery patients compared to GA.
Study context
- Population
- Patients undergoing hip fracture surgery12 RCTs
- Comparison
- Regional anesthesia (RA) vs general anesthesia (GA)
- Outcome
- 30-day mortality
- Follow-up
- 30 days
Methodological detailsrandom-effects model, subgroup analyses by study design
- Random-effects model
- Subgroup analyses by study design
Pooled result
As reported in the abstract
Odds ratio
0.88
95% CI 0.44–1.74
RA vs GA
OR 0.88 (95% CI 0.44–1.74)
Further pooled results
90-day mortality, in-hospital mortality, length of surgery, length of hospital stay
- No significant differences
Safety
| Outcome | OR (95% CI) | |
|---|---|---|
| Intraoperative hypotensionI2 = 0% | 0.52 (0.38–0.72) | |
| 0.20.5125Odds ratio (log scale) |
Postoperative delirium, pneumonia, MI, VTE
- No significant differences
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Comparing perioperative outcomes between regional anesthesia and general anesthesia in patients undergoing hip fracture surgery: a systematic review and meta-analysis. Can J Anaesth. Published 28 February 2024. doi:10. 1007/ s12630-024-02696-3
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