Perioperative medicine & outcomes

Comparing perioperative outcomes between regional anesthesia and general anesthesia in patients undergoing hip fracture surgery: a systematic review and meta-analysis

Can J AnaesthPublished Systematic review and meta-analysis of randomised trials

Pooled result · 30-day mortalityResult — go to the resultOdds ratio 0.88 95% CI 0.44–1.74

Authors' conclusion

In this updated systematic review and meta-analysis, RA did not reduce postoperative 30-day mortality in hip fracture surgery patients compared to GA.

Study context

Population
Patients undergoing hip fracture surgery12 RCTs
Comparison
Regional anesthesia (RA) vs general anesthesia (GA)
Outcome
30-day mortality
Follow-up
30 days
Methodological detailsrandom-effects model, subgroup analyses by study design
  • Random-effects model
  • Subgroup analyses by study design

Pooled result

As reported in the abstract

Odds ratio

0.88

95% CI 0.44–1.74

RA vs GA
OR 0.88 (95% CI 0.44–1.74)

Further pooled results

90-day mortality, in-hospital mortality, length of surgery, length of hospital stay

No significant differences

Safety

OutcomeOR (95% CI)
Intraoperative hypotensionI2 = 0%0.52 (0.38–0.72)

Postoperative delirium, pneumonia, MI, VTE

No significant differences

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Comparing perioperative outcomes between regional anesthesia and general anesthesia in patients undergoing hip fracture surgery: a systematic review and meta-analysis. Can J Anaesth. Published 28 February 2024. doi:10.1007/s12630-024-02696-3

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