Hemodynamics, fluids & transfusion
Comparing the compensatory reserve metric obtained from invasive arterial measurements and photoplethysmographic volume-clamp during simulated hemorrhage
Authors' conclusion
There is generally good agreement between CRM values obtained from invasive arterial waveforms and values obtained from PPGVC waveforms.
Study context
- Population
- Participants undergoing graded lower body negative pressure to simulate hemorrhage
- Participants
- 69 participants
- Comparison
- Compensatory reserve metric (CRM) from invasive arterial waveforms vs PPGVC brachial and PPGVC finger waveforms
- Outcome
- Agreement of CRM values (Bland-Altman mean bias [95% limits of agreement])
Methodological detailsBland-Altman analysis, simulated hemorrhage (graded lower body negative pressure), CRM computed by a deep one-dimensional convolutional neural network
- Bland-Altman analysis
- Simulated hemorrhage (graded lower body negative pressure)
- CRM computed by a deep one-dimensional convolutional neural network
Main finding
As reported in the abstract
CRM agreement, mean bias [95% limits of agreement]
Mean bias, %
- PPGVC brachial · at rest
- 6 (95% limits of agreement CI −17% to 29%)
- PPGVC brachial · −45mmHg
- 1 (95% limits of agreement CI −28% to 30%)
- PPGVC brachial · at tolerance
- 0 (95% limits of agreement CI −25% to 25%)
- PPGVC finger · at rest
- 2 (95% limits of agreement CI −22% to 26%)
- PPGVC finger · −45mmHg
- 8 (95% limits of agreement CI −19% to 35%)
- PPGVC finger · at tolerance
- 5 (95% limits of agreement CI −15% to 25%)
Original publication
Comparing the compensatory reserve metric obtained from invasive arterial measurements and photoplethysmographic volume-clamp during simulated hemorrhage. J Clin Monit Comput. Published 11 May 2024. doi:10.
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