Comparison of 1% chloroprocaine hydrochloride versus hyperbaric bupivacaine spinal in patients undergoing anorectal surgery in an ambulatory surgery center: a double-blind randomized clinical trial
Authors' conclusion
Our study demonstrated a significantly reduced time to meeting discharge criteria with chloroprocaine compared with bupivacaine without an increased risk of TNS.
Study context
- Population
- Patients undergoing ambulatory anorectal surgery in an ambulatory surgery center5 excluded (spinal failure)
- Participants
- 110 patients
- Comparison
- 1% chloroprocaine vs 0.75% bupivacaine spinal anaesthesia
- Primary endpoint
- Co-primary: recovery time (return of motor and sensory function) and time to meet discharge criteria
Methodological detailsdouble-blind
- Double-blind
Primary result
As reported in the abstract
Time to meet discharge criteria; recovery time
P = <0.001
Safety
Transient neurological symptoms (TNS) · within 24 hours after the procedure
- No TNS recorded in either group
Original publication
Comparison of 1% chloroprocaine hydrochloride versus hyperbaric bupivacaine spinal in patients undergoing anorectal surgery in an ambulatory surgery center: a double-blind randomized clinical trial. Reg Anesth Pain Med. Published 31 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →