Cardiothoracic & vascular anesthesia
Comparison between costotransverse foramen block and thoracic paravertebral block for video-assisted thoracoscopic surgery (VATS) pulmonary resection: A randomized noninferiority trial
Primary result · 24-h AUC of NRSResult — go to the resultDifference −5.27 95% CI −15.09 to 4.55Authors' conclusion
The analgesic effect of CTFB was noninferior to that of TPVB during 24 h postoperatively in VATS pulmonary resection.
Study context
- Population
- Patients aged 20 to 80 years, ASA 1 to 3, scheduled for elective VATS pulmonary resection47 analysed
- Participants
- Sixty patients
- Comparison
- Costotransverse foramen block (CTFB) vs thoracic paravertebral block (TPVB)
- CTFBn = 24
- TPVBn = 23reference
- Primary endpoint
- AUC of numeric rating scale (NRS) (0 to 10) pain (noninferiority limit 24; NRS 1 per hour)
- Follow-up
- 24 h postoperatively
Methodological detailssingle-centre, double-blinded, non-inferiority
- Single-centre
- Double-blinded
- Non-inferiority
Primary result
24-h AUC of NRS
Difference
−5.27
95% CI −15.09 to 4.55
By group
CTFB
34.25
mean · SD 16.30
TPVB
39.52
mean · SD 17.13
CTFB vs TPVB
difference −5.27 (95% CI −15.09 to 4.55)
Non-inferiority margin 24 as printed, not drawn
As reported in the abstract
Secondary outcomes
Dermatomal spread of the blockade
- No significant difference; both reached upper and lower most levels of T3 and T7 (median)
Opioid consumption, rescue analgesic use, PONV, pulmonary function, quality of recovery
- No significant differences between the two groups
Original publication
Comparison between costotransverse foramen block and thoracic paravertebral block for VATS pulmonary resection: A randomized noninferiority trial. J Clin Anesth. Published 17 May 2023. doi:10.
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